Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FRK | P42685 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26119367 | 1.00 | TGFBR1 (0.43) | TGFBR1ROCK1MAPK14IKBKBMAPK13 | |
| SCHEMBL30581008 | 0.93 | MAPK14 (0.46) | TGFBR1MAPK14IKBKBMAPK13PRKD3 | |
| SCHEMBL26119712 | 0.93 | MAPK14 (0.46) | TGFBR1MAPK14IKBKBMAPK13PRKD3 | |
| SCHEMBL26118897 | 0.93 | MAPK14 (0.38) | TGFBR1MAPK14IKBKBMAPK13PRKD3 | |
| SCHEMBL30580871 | 0.93 | MAPK14 (0.38) | TGFBR1MAPK14IKBKBMAPK13PRKD3 | |
| SCHEMBL26121656 | 0.91 | TGFBR1 (0.38) | TGFBR1MAPK14IKBKBMAPK13PRKD3 | |
| SCHEMBL31377941 | 0.91 | TGFBR1 (0.42) | TGFBR1MAPK14IKBKBMAPK13PRKD3 | |
| SCHEMBL26123842 | 0.91 | TGFBR1 (0.42) | TGFBR1MAPK14IKBKBMAPK13PRKD3 | |
| SCHEMBL30580771 | 0.90 | RAF1 (0.41) | TGFBR1MAPK14IKBKBMAPK13PRKD3 | |
| SCHEMBL26124644 | 0.90 | RAF1 (0.41) | TGFBR1MAPK14IKBKBMAPK13PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119255993-A | Thiazole derivative compound and use thereof | 奥托泰利克生物公司 | 2025-01-03 | — | — | CN | claimed |
| WO-2023182780-A1 | THIAZOLE DERIVATIVE COMPOUND AND USES THEREOF | 오토텔릭바이오 주식회사 | 2023-09-28 | — | — | WO | claimed |
| CN-119255993-A | Thiazole derivative compound and use thereof | 奥托泰利克生物公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2023182780-A1 | THIAZOLE DERIVATIVE COMPOUND AND USES THEREOF | 오토텔릭바이오 주식회사 | 2023-09-28 | — | — | WO | disclosed |