Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.84 |
| ▸ | LPAR1 | Q92633 | 10/20 | 0.84 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.62 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989870 | 1.00 | LPAR3 (0.84) | LPAR3LPAR1LPAR2LPAR5ENPP2 | |
| SCHEMBL23148274 | 1.00 | LPAR3 (0.84) | LPAR3LPAR1LPAR2LPAR5ENPP2 | |
| SCHEMBL11325872 | 0.96 | LPAR3 (0.78) | LPAR3LPAR1LPAR2LPAR5ENPP2 | |
| SCHEMBL11325869 | 0.96 | LPAR3 (0.78) | LPAR3LPAR1LPAR2LPAR5ENPP2 | |
| SCHEMBL31281823 | 0.95 | LPAR3 (0.75) | LPAR3LPAR1LPAR2LPAR5ENPP2 | |
| Monoethanolamine SCHEMBL29057722 | 0.93 | LPAR3 (0.72) | LPAR3LPAR1LPAR2LPAR5ENPP2 | |
| SCHEMBL5055004 | 0.92 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5ENPP2 | |
| SCHEMBL10896195 | 0.92 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5ENPP2 | |
| SCHEMBL2814732 | 0.92 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5ENPP2 | |
| SCHEMBL31439420 | 0.92 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651771-A | TMPRSS6 targeted siRNA for treatment of myeloproliferative disorders | 赛伦斯治疗有限责任公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-116802290-A | Nucleic acids for inhibiting PROS1 expression in cells | 伯尔尼大学 | 2023-09-22 | — | — | CN | disclosed |