Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 1.00 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.64 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.64 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.64 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.61 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.61 |
| ▸ | PRKCG | P05129 | 1/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | LYN | P07948 | 1/20 | 0.61 |
| ▸ | RET | P07949 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | PRKACA | P17612 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | FLT4 | P35916 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323457 | 1.00 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL20551142 | 0.96 | MAPK14 (0.92) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL20550892 | 0.95 | MAPK14 (0.90) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL23795652 | 0.92 | MAPK14 (0.84) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL20550895 | 0.83 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL4323452 | 0.82 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL29842089 | 0.81 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL23795663 | 0.81 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL4916578 | 0.81 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL30023277 | 0.81 | MAPK14 (0.87) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |