Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.84 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.57 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.57 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.57 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.57 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.55 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | PRKCG | P05129 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | LYN | P07948 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583155 | 0.92 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL4323457 | 0.92 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL20551142 | 0.90 | MAPK14 (0.92) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL20550892 | 0.89 | MAPK14 (0.90) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL28610584 | 0.84 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL23795664 | 0.84 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL29842093 | 0.82 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL23795642 | 0.82 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL20550895 | 0.78 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL29841893 | 0.78 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272298-B | Compounds and compositions for the treatment of respiratory diseases | 天莅生物技术有限公司 | 2025-04-18 | — | — | CN | disclosed |
| US-20220281846-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASES | TIANLI BIOTECH PTY LTD (AU) | 2022-09-08 | — | — | US | disclosed |
| EP-3877383-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASES | The University of Melbourne (AU) | 2021-09-15 | — | — | EP | disclosed |
| CN-113272298-A | Compounds and compositions for the treatment of respiratory diseases | 墨尔本大学 | 2021-08-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281846-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASES | LTC4S, CCL11, LTB4R2 | MAPK14 3737/4885MAPK13 2970/4885MAPK12 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.