Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24913011 | 0.99 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL26880870 | 0.99 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL26662647 | 0.89 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL26662643 | 0.89 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL30584420 | 0.89 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL26662629 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL31316385 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL24912996 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL31035409 | 0.86 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL31035111 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514784-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023212693-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2023-11-02 | — | — | WO | disclosed |