Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | PDE4A | P27815 | 2/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25433010 | 1.00 | MAPT (0.62) | MAPTPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL30584782 | 1.00 | MAPT (0.62) | MAPTPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL30584777 | 0.88 | MAPT (0.61) | MAPTMEN1KMT2AGRM5TP53 | |
| SCHEMBL25433079 | 0.88 | MAPT (0.61) | MAPTMEN1KMT2AGRM5TP53 | |
| SCHEMBL25433461 | 0.86 | MAPT (0.58) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL25435216 | 0.83 | GRM5 (0.53) | MAPTNOTUMMEN1KMT2AGRM5 | |
| SCHEMBL30584813 | 0.83 | GRM5 (0.53) | MAPTPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL25402964 | 0.83 | GRM5 (0.53) | MAPTPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL30584787 | 0.83 | GRM5 (0.53) | MAPTNOTUMMEN1KMT2AGRM5 | |
| SCHEMBL25401997 | 0.80 | MEN1 (0.65) | MAPTPDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463452-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023177700-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2023-09-21 | — | — | WO | disclosed |