Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | LCLAT1 | Q6UWP7 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24473959 | 1.00 | SMO (0.72) | SMOMEN1KMT2ATDP1LCLAT1 | |
| SCHEMBL13878308 | 0.88 | MEN1 (0.60) | SMOMEN1KMT2ATDP1LCLAT1 | |
| SCHEMBL20522049 | 0.88 | LCLAT1 (0.80) | LCLAT1KDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL30587145 | 0.84 | SMO (1.00) | SMOLCLAT1MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL26078521 | 0.84 | SMO (0.72) | SMOMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL16384061 | 0.84 | SMO (1.00) | SMOLCLAT1MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL4033854 | 0.83 | NPC1 (0.58) | SMORAB9ANPC1KDM4EMAPT | |
| SCHEMBL4241242 | 0.82 | CHRNA7 (0.53) | SMOMEN1KMT2ATDP1KDM4E | |
| SCHEMBL24473971 | 0.81 | ADCY1 (0.74) | SMOMEN1KMT2ATDP1RAB9A | |
| SCHEMBL24474016 | 0.80 | LCLAT1 (0.68) | SMOMEN1KMT2ALCLAT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457353-A | N-substituted 4- (5-phenyl-1, 3, 4-oxadiazol-2-yl) anilines for the treatment and prophylaxis of hepatitis b virus infections | 豪夫迈·罗氏有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-116457353-A | N-substituted 4- (5-phenyl-1, 3, 4-oxadiazol-2-yl) anilines for the treatment and prophylaxis of hepatitis b virus infections | 豪夫迈·罗氏有限公司 | 2023-07-18 | — | — | CN | disclosed |