Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26530944 | 0.91 | ATR (0.46) | ATREGLN2CYP17A1AAK1MAPKAPK2 | |
| SCHEMBL31278566 | 0.91 | ATR (0.46) | ATREGLN2CYP17A1AAK1MAPKAPK2 | |
| SCHEMBL26118724 | 0.85 | ATR (0.51) | ATRSREBF2CYP17A1LCK | |
| SCHEMBL30587238 | 0.85 | ATR (0.51) | ATRSREBF2CYP17A1LCK | |
| SCHEMBL30587290 | 0.78 | LCK (0.34) | ATRMAPKAPK2LCKALDH1A1TSHR | |
| SCHEMBL26117868 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10KDM4EHPGD | |
| SCHEMBL26530970 | 0.72 | LCK (0.37) | ATRMAPKAPK2LCKALDH1A1TSHR | |
| SCHEMBL30776330 | 0.72 | LCK (0.37) | ATRMAPKAPK2LCKALDH1A1TSHR | |
| SCHEMBL30587220 | 0.71 | ATR (0.35) | ATREGLN2MAPKAPK2LCKALDH1A1 | |
| SCHEMBL26119259 | 0.71 | ATR (0.35) | ATREGLN2MAPKAPK2LCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499233-A1 | KRAS INHIBITORS | Eli Lilly and Company (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183585-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-09-28 | — | — | WO | disclosed |