Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.30 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26119259 | 0.87 | ATR (0.35) | ALDH1A1NPC1RAB9ATP53MAPT | |
| SCHEMBL30587220 | 0.87 | ATR (0.35) | ALDH1A1NPC1RAB9ATP53MAPT | |
| SCHEMBL26118191 | 0.84 | MEN1 (0.34) | ALDH1A1NPC1RAB9AALOX15MAPK1 | |
| SCHEMBL26114309 | 0.84 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9AALOX15MAPK1 | |
| SCHEMBL30587219 | 0.84 | MEN1 (0.34) | ALDH1A1NPC1RAB9AALOX15MAPK1 | |
| SCHEMBL30587281 | 0.84 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9AALOX15MAPK1 | |
| SCHEMBL26530970 | 0.79 | LCK (0.37) | ALDH1A1NPC1RAB9ATP53MAPT | |
| SCHEMBL30776330 | 0.79 | LCK (0.37) | ALDH1A1NPC1RAB9ATP53MAPT | |
| SCHEMBL31085630 | 0.77 | LCK (0.35) | ALDH1A1NPC1RAB9AALOX15MAPK1 | |
| SCHEMBL31491061 | 0.76 | EGLN2 (0.35) | ALDH1A1NPC1RAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499233-A1 | KRAS INHIBITORS | Eli Lilly and Company (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183585-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-09-28 | — | — | WO | disclosed |