⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005969 | 1.00 | — | — | |
| SCHEMBL305900 | 1.00 | — | — | |
| SCHEMBL2343201 | 0.77 | — | — | |
| SCHEMBL12391217 | 0.77 | — | — | |
| SCHEMBL517745 | 0.73 | GAA (0.31) | — | |
| SCHEMBL517744 | 0.73 | GAA (0.31) | — | |
| SCHEMBL13049304 | 0.71 | — | — | |
| SCHEMBL24631878 | 0.71 | GAA (0.30) | — | |
| SCHEMBL517616 | 0.71 | CPB2 (0.30) | — | |
| SCHEMBL1007032 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594308-A1 | N-ACRYLOYLMORPHOLINE DERIVATIVES AS KEAP1 MODULATORS AND USES THEREOF | Vividion Therapeutics, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| US-20250205219-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS AG (CH) | 2025-06-26 | — | — | US | disclosed |
| EP-4291552-B1 | MODULATORS OF COMPLEX I | BOEHRINGER INGELHEIM INT (DE) | 2025-04-09 | — | — | EP | disclosed |
| US-12257247-B2 | Targeted degradation of VAV1 | MONTE ROSA THERAPEUTICS AG (CH) | 2025-03-25 | — | — | US | disclosed |
| CN-119431378-A | Ring-fused compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-12202836-B2 | Bicyclic-fused heteroaryl or aryl compounds | PFIZER INC. (US) | 2025-01-21 | — | — | US | disclosed |
| US-20240285604-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS AG (CH) | 2024-08-29 | — | — | US | disclosed |
| US-12071403-B2 | Modulators of complex I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-08-27 | — | — | US | disclosed |
| WO-2024160058-A1 | OXALIC ACID DIAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 四川科伦博泰生物医药股份有限公司 | 2024-08-08 | — | — | WO | disclosed |
| US-20240226114-A1 | INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
| US-5002937-A | Diphosphonic acid alkyloxyalkylamines for bone disorders | BOEHRINGER MANNHEIM GMBH (DE) | 1991-03-26 | — | — | US | disclosed |
| EP-0350002-A1 | Diphosphonic-acid derivatives, process for their preparation and medicines containing those compounds | Roche Diagnostics GmbH (DE) | 1990-01-10 | — | — | EP | disclosed |
| US-4882359-A | USED WITH DRUGS | HISAMITSU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| WO-1987006226-A2 | AZACYCLOALKANE DERIVATIVES, ABSORPTION PROMOTERS CONTAINING THE DERIVATIVES AS THE EFFECTIVE INGREDIENT AND EXTERNAL PREPARATIONS CONTAINING THE ABSORPTION PROMOTERS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1987-10-22 | — | — | WO | disclosed |
| CN-87100666-A | Nitrogen heterocyclic derivative, absorption enhancer containing the derivative as active ingredient, and external preparation containing the absorption enhancer | — | 1987-10-21 | — | — | CN | disclosed |
| EP-0241050-A2 | Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparation containing the absorption promoters | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1987-10-14 | — | — | EP | disclosed |
| US-4058462-A | System for sustained release of phenolic material from porous granules of insoluble polymeric phenolic complexes | GAF CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-3985540-A | Metal complexes of hydroxyquinoline and polymeric porous granules | GAF CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |
| US-3970606-A | N-vinyl lactam interpolymers useful as thickening agents | GAF CORPORATION (US) | 1976-07-20 | — | — | US | disclosed |
| US-3954682-A | GRANULES OR BEADS | GAF CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |