Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104844 | 0.85 | EPHX2 (0.51) | EPHX2SCN7AKCNH2SCN9AADRB1 | |
| SCHEMBL31474533 | 0.85 | EPHX2 (0.51) | EPHX2SCN7AKCNH2SCN9AADRB1 | |
| SCHEMBL30591805 | 0.79 | SMN1; SMN2 (0.48) | SCN9ALIPEBCHESMN1; SMN2CYP3A4 | |
| SCHEMBL26104579 | 0.79 | MAPT (0.41) | SCN9ALIPEBCHEKMT2ASMN1; SMN2 | |
| SCHEMBL26107556 | 0.79 | SMN1; SMN2 (0.48) | SCN9ALIPEBCHESMN1; SMN2CYP3A4 | |
| SCHEMBL27505893 | 0.77 | HTR2C (0.47) | EPHX2ADRB2NCF1 | |
| SCHEMBL26134573 | 0.76 | EPHX2 (0.47) | EPHX2ADRB1 | |
| SCHEMBL30591932 | 0.76 | EPHX2 (0.47) | EPHX2SCN9ASCN10AADRB1 | |
| SCHEMBL26134481 | 0.76 | EPHX2 (0.47) | EPHX2SCN9ASCN10AADRB1 | |
| SCHEMBL26107260 | 0.76 | HTR2C (0.47) | SCN7AKCNH2SCN9ASCN5ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4496570-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | The Scripps Research Institute (US) | 2025-01-29 | — | — | EP | disclosed |
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |