Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104844 | 1.00 | EPHX2 (0.51) | EPHX2ADRB1ADRB2NCF1SCN7A | |
| SCHEMBL26108850 | 0.88 | ALDH1A1 (0.43) | EPHX2PDE10ATRPV1TRPA1 | |
| SCHEMBL30591953 | 0.88 | ALDH1A1 (0.43) | EPHX2PDE10ATRPV1TRPA1 | |
| SCHEMBL30591932 | 0.85 | EPHX2 (0.47) | EPHX2ADRB1SCN9APDE10A | |
| SCHEMBL26134481 | 0.85 | EPHX2 (0.47) | EPHX2ADRB1SCN9APDE10A | |
| SCHEMBL30592002 | 0.85 | EPHX2 (0.47) | EPHX2ADRB1ADRB2NCF1SCN7A | |
| SCHEMBL26134573 | 0.83 | EPHX2 (0.47) | EPHX2ADRB1HTR2C | |
| SCHEMBL27505893 | 0.81 | HTR2C (0.47) | EPHX2ADRB2NCF1HTR2C | |
| SCHEMBL3321164 | 0.79 | EPHX2 (0.55) | EPHX2ADRB1ADRB2NCF1KCNH2 | |
| SCHEMBL30591874 | 0.77 | TRPV1 (0.52) | PDE10ATRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250206722-A1 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE | 2025-06-26 | — | — | US | disclosed |
| CN-119403551-A | Small molecule inhibitors of TEA domain family members | 斯克里普斯研究学院 | 2025-02-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206722-A1 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | YAP1, TEAD1, TEAD2 | EPHX2 4238/4885ADRB1 2436/4885ADRB2 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.