Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269634 | 1.00 | ROCK1 (0.32) | ROCK1LRRK2 | |
| SCHEMBL25230025 | 0.74 | FLT3 (0.40) | — | |
| SCHEMBL29536830 | 0.74 | FLT3 (0.40) | — | |
| SCHEMBL24457858 | 0.71 | LRRK2 (0.35) | LRRK2 | |
| SCHEMBL27527903 | 0.69 | LRRK2 (0.41) | LRRK2 | |
| SCHEMBL25227840 | 0.68 | SIK2 (0.38) | — | |
| SCHEMBL30078181 | 0.67 | WEE1 (0.45) | — | |
| SCHEMBL24885507 | 0.67 | WEE1 (0.45) | — | |
| SCHEMBL30595898 | 0.67 | PIK3CA (0.36) | — | |
| SCHEMBL25230887 | 0.67 | PIK3CA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |