Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.69 |
| ▸ | PDE1A | P54750 | 9/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 9/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 9/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596250 | 0.81 | PDE4D (1.00) | PDE4DPDE1APDE1BPDE1CPDE4B | |
| SCHEMBL30596256 | 0.79 | PDE4D (1.00) | PDE4DPDE1APDE1BPDE1C | |
| SCHEMBL30596269 | 0.77 | PDE4D (0.67) | PDE4DPDE1APDE1BPDE1CMAPK1 | |
| SCHEMBL30596273 | 0.74 | PDE4D (0.85) | PDE4DPDE1APDE1BPDE1CMAPK1 | |
| SCHEMBL30596262 | 0.74 | PDE4D (0.62) | PDE4DPDE1APDE1BPDE1CMAPK1 | |
| SCHEMBL30984353 | 0.67 | PDE4B (0.49) | PDE4DPDE4B | |
| SCHEMBL30596258 | 0.67 | PDE4D (0.73) | PDE4DPDE1APDE1BPDE1CMAPK1 | |
| SCHEMBL12499545 | 0.67 | EZH2 (0.59) | PDE4DPDE1APDE1BPDE1CPDE4B | |
| SCHEMBL17963332 | 0.65 | PDE4B (0.57) | PDE4DPDE4B | |
| SCHEMBL23530017 | 0.65 | PDE4D (0.41) | PDE4DPDE1APDE1BPDE1CMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |