Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.62 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 13/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 11/20 | 0.40 |
| ▸ | PDE1A | P54750 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596269 | 0.83 | PDE4D (0.67) | PDE4DPDE1BPDE1CPDE1AMAPK1 | |
| SCHEMBL30596250 | 0.77 | PDE4D (1.00) | PDE4DPDE1BPDE1CPDE1A | |
| SCHEMBL30596256 | 0.75 | PDE4D (1.00) | PDE4DPDE1BPDE1CPDE1A | |
| SCHEMBL30596248 | 0.74 | PDE4D (0.69) | PDE4DPDE1BPDE1CPDE1AMAPK1 | |
| SCHEMBL30596273 | 0.70 | PDE4D (0.85) | PDE4DPDE1BPDE1CPDE1AMAPK1 | |
| SCHEMBL30596258 | 0.63 | PDE4D (0.73) | PDE4DPDE1BPDE1CPDE1AMAPK1 | |
| SCHEMBL17485775 | 0.62 | PDE4D (0.49) | PDE4DPDE1BPDE1CPDE1A | |
| SCHEMBL15440751 | 0.62 | PDE10A (0.49) | PDE4DPDE1BPDE1CPDE1AMAPK1 | |
| SCHEMBL31195616 | 0.62 | PDE10A (0.49) | PDE4DPDE1BPDE1CPDE1AMAPK1 | |
| SCHEMBL16985495 | 0.61 | LRRK2 (0.54) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |