Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.54 |
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CLK1 | P49759 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30597557 | 0.94 | MAPT (0.65) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30597537 | 0.91 | MAPT (0.63) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30597528 | 0.90 | MAPT (0.73) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30597492 | 0.88 | MAPT (0.62) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30597508 | 0.88 | MAPT (0.66) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30597504 | 0.88 | MAPT (0.63) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30597531 | 0.87 | MEN1 (0.61) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30597532 | 0.87 | MAPT (0.70) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30597555 | 0.85 | MAPT (0.68) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30597501 | 0.85 | MAPT (0.65) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023201014-A1 | BENZOTHIAZOLE-PHENYLSULFONYL-PIPERIDINE ANALOGS AS ACTIVATORS OF N-ACYLPHOSPHATIDYLETHANOLAMINE HYDROLYZING PHOSPHOLIPASE D | VANDERBILT UNIVERSITY (US) | 2023-10-19 | — | — | WO | claimed |
| WO-2023201014-A1 | BENZOTHIAZOLE-PHENYLSULFONYL-PIPERIDINE ANALOGS AS ACTIVATORS OF N-ACYLPHOSPHATIDYLETHANOLAMINE HYDROLYZING PHOSPHOLIPASE D | VANDERBILT UNIVERSITY (US) | 2023-10-19 | — | — | WO | disclosed |