Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30597496 | 0.90 | EPHX2 (0.60) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL30597543 | 0.89 | MEN1 (0.63) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL30597555 | 0.87 | MAPT (0.68) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL30597493 | 0.86 | MEN1 (0.60) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL30597506 | 0.86 | MEN1 (0.62) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL30597531 | 0.85 | MEN1 (0.61) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL30597554 | 0.85 | MEN1 (0.61) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL30597541 | 0.85 | MEN1 (0.61) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL30597550 | 0.84 | MEN1 (0.59) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL30597500 | 0.84 | L3MBTL1 (0.63) | NPC1RAB9AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023201014-A1 | BENZOTHIAZOLE-PHENYLSULFONYL-PIPERIDINE ANALOGS AS ACTIVATORS OF N-ACYLPHOSPHATIDYLETHANOLAMINE HYDROLYZING PHOSPHOLIPASE D | VANDERBILT UNIVERSITY (US) | 2023-10-19 | — | — | WO | disclosed |