Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678371 | 0.83 | PDE1B (0.42) | PTPN1SMN1; SMN2BLMPMP22KDM4E | |
| SCHEMBL19280469 | 0.81 | PDE1B (0.42) | SMN1; SMN2KDM4ENPC1LMNAMAPT | |
| SCHEMBL19701834 | 0.79 | CSF1R (0.41) | SMN1; SMN2L3MBTL1NPC1LMNAMAPT | |
| SCHEMBL12283605 | 0.77 | GAA (0.39) | PTPN1SMN1; SMN2KDM4EL3MBTL1POLB | |
| SCHEMBL14652253 | 0.74 | GAA (0.38) | PTPN1SMN1; SMN2KDM4EL3MBTL1NPC1 | |
| SCHEMBL30523344 | 0.74 | ROCK2 (0.38) | SMN1; SMN2KDM4ENPC1RAB9ALMNA | |
| SCHEMBL19354353 | 0.71 | PDE1B (0.44) | SMN1; SMN2KDM4ENPC1RAB9ALMNA | |
| SCHEMBL21199274 | 0.70 | PDE2A (0.41) | PTPN1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL10250615 | 0.70 | TSHR (0.53) | SMN1; SMN2KDM4ELMNAMAPTUSP2 | |
| SCHEMBL12283712 | 0.69 | GAA (0.40) | PTPN1SMN1; SMN2KDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903626-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-10-20 | — | — | CN | disclosed |