Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 9/20 | 0.38 |
| ▸ | ITK | Q08881 | 7/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 3/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30599491 | 1.00 | TGM2 (0.40) | TGM2EGFRITKGSTO1KDR | |
| SCHEMBL25393645 | 1.00 | TGM2 (0.40) | TGM2EGFRITKGSTO1KDR | |
| SCHEMBL31539696 | 0.82 | TGM2 (0.36) | TGM2EGFRITKGSTO1KDR | |
| SCHEMBL30599515 | 0.79 | FGFR4 (0.39) | EGFRITKBTKFGFR4 | |
| SCHEMBL25391794 | 0.79 | FGFR4 (0.39) | EGFRITKBTKFGFR4 | |
| SCHEMBL25294152 | 0.78 | TGM2 (0.46) | TGM2GSTO1BTKFGFR4 | |
| SCHEMBL31539844 | 0.78 | DAO (0.34) | FGFR4 | |
| SCHEMBL25247069 | 0.74 | TGM2 (0.46) | TGM2ITKGSTO1KDRTEK | |
| SCHEMBL29410354 | 0.74 | TGM2 (0.46) | TGM2ITKGSTO1KDRTEK | |
| SCHEMBL31539782 | 0.72 | TGM2 (0.44) | TGM2EGFRITKKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486721-A1 | ACRYLAMIDE COMPOUNDS | NRG Therapeutics LTD (GB) | 2025-01-08 | — | — | EP | disclosed |
| CN-118804911-A | Acrylamide compound | NRG治疗有限公司 | 2024-10-18 | — | — | CN | disclosed |
| WO-2023166303-A1 | ACRYLAMIDE COMPOUNDS | NRG THERAPEUTICS LTD (GB) | 2023-09-07 | — | — | WO | disclosed |