Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797503 | 0.89 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL21827063 | 0.80 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL31635992 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL10807598 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL20566310 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL1505008 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL13164434 | 0.75 | SMN1; SMN2 (0.56) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL24214317 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL26931780 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL12344745 | 0.74 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116887831-A | Factor XIa inhibitors | 默沙东有限责任公司 | 2023-10-13 | — | — | CN | disclosed |