Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269102 | 1.00 | RET (0.40) | RETAAK1KIF18APDE10AKDM4D | |
| SCHEMBL30599741 | 0.85 | RET (0.48) | RETAAK1KIF18APDE10AKDM4D | |
| SCHEMBL29418549 | 0.85 | RET (0.48) | RETAAK1KIF18APDE10AKDM4D | |
| SCHEMBL29418386 | 0.83 | KDM4D (0.43) | RETAAK1KIF18APDE10AKDM4D | |
| SCHEMBL30599716 | 0.83 | KDM4D (0.43) | RETAAK1KIF18APDE10AKDM4D | |
| SCHEMBL29418780 | 0.83 | KDM4D (0.43) | RETAAK1KIF18APDE10AKDM4D | |
| SCHEMBL29418791 | 0.80 | KDM4D (0.43) | RETAAK1KIF18APDE10AKDM4D | |
| SCHEMBL38665924 | 0.80 | RET (0.46) | RETAAK1KIF18APDE10AKDM4D | |
| SCHEMBL38666676 | 0.80 | RET (0.46) | RETAAK1KIF18APDE10AKDM4D | |
| SCHEMBL29418476 | 0.80 | RET (0.42) | RETAAK1KIF18APDE10AKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |