SCHEMBL30599741 — predicted protein targets

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	RET	P07949	5/20	0.48

▸	JAK3	P52333	3/20	0.40

▸	BTK	Q06187	2/20	0.40

▸	LCK	P06239	1/20	0.39

▸	GPR119	Q8TDV5	4/20	0.38

▸	AAK1	Q2M2I8	1/20	0.37

▸	KIF18A	Q8NI77	1/20	0.37

▸	PDE10A	Q9Y233	1/20	0.36

▸	KDM4D	Q6B0I6	1/20	0.36

▸	SPR	P35270	1/20	0.36

▸	JAK2	O60674	1/20	0.35

▸	HSD11B1	P28845	1/20	0.35

▸	NR1H2	P55055	1/20	0.35

▸	NR1H3	Q13133	1/20	0.35

▸	CSNK2A2	P19784	1/20	0.34

▸	CSNK2B	P67870	1/20	0.34

▸	CSNK2A1	P68400	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29418549	1.00	RET (0.48)	RETJAK3BTKLCKGPR119
SCHEMBL25252910	0.86	JAK2 (0.38)	RETJAK3BTKJAK2CSNK2A2
SCHEMBL25252907	0.86	JAK2 (0.38)	RETJAK3BTKJAK2CSNK2A2
SCHEMBL30599747	0.85	RET (0.40)	RETJAK3BTKLCKAAK1
SCHEMBL25269102	0.85	RET (0.40)	RETJAK3BTKLCKAAK1
SCHEMBL29418386	0.81	KDM4D (0.43)	RETJAK3BTKLCKGPR119
SCHEMBL29418780	0.81	KDM4D (0.43)	RETJAK3BTKLCKGPR119
SCHEMBL30599716	0.81	KDM4D (0.43)	RETJAK3BTKLCKGPR119
SCHEMBL29418791	0.78	KDM4D (0.43)	RETGPR119AAK1KIF18APDE10A
SCHEMBL38665924	0.77	RET (0.46)	RETJAK3BTKLCKAAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116917279-A	BTK inhibitors	渤健马萨诸塞州股份有限公司	2023-10-20	—	—	CN	disclosed