Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30599785 | 0.83 | ALDH1A1 (0.44) | MAPTTDP1SMN1; SMN2TSHRLMNA | |
| SCHEMBL14711327 | 0.82 | SLC5A1 (0.48) | MAPTSMN1; SMN2TSHRALDH1A1RAB9A | |
| SCHEMBL2358435 | 0.82 | KMT2A (0.58) | MAPTLMNAALDH1A1KDM4EMAPK1 | |
| SCHEMBL13624226 | 0.82 | PDE4D (0.58) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL9681622 | 0.82 | ALDH1A1 (0.57) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL27588720 | 0.81 | KDM4C (0.35) | MAPTTDP1SMN1; SMN2TSHRLMNA | |
| SCHEMBL3228828 | 0.81 | SLC34A1 (0.49) | MAPTTDP1SMN1; SMN2TSHRLMNA | |
| SCHEMBL16099572 | 0.81 | MAPT (0.47) | MAPTTDP1SMN1; SMN2TSHRLMNA | |
| SCHEMBL19640088 | 0.79 | KDM4C (0.43) | ALDH1A1KDM4ENPSR1POLBHPGD | |
| SCHEMBL6180486 | 0.78 | ALDH1A1 (0.56) | MAPTSMN1; SMN2TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696037-A | Azacyclic amide derivatives, preparation method and medical application thereof | 翰森生物有限责任公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-111655692-B | Nitrogen-containing heterocyclic amide compound and medical application thereof | 日本烟草产业株式会社 | 2023-10-10 | — | — | CN | disclosed |