Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.62 |
| ▸ | GSPT1 | P15170 | 8/20 | 0.62 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751108 | 1.00 | CRBN (0.62) | CRBNDDB1GSPT1IKZF3EPHX2 | |
| SCHEMBL21751065 | 0.94 | CRBN (0.62) | CRBNDDB1GSPT1IKZF3EPHX2 | |
| SCHEMBL30600392 | 0.93 | CRBN (0.55) | CRBNDDB1GSPT1IKZF3RAB9A | |
| SCHEMBL21751087 | 0.93 | CRBN (0.55) | CRBNDDB1GSPT1IKZF3RAB9A | |
| SCHEMBL21751070 | 0.90 | CRBN (0.53) | CRBNDDB1GSPT1IKZF3SMN1; SMN2 | |
| SCHEMBL30600436 | 0.90 | CRBN (0.53) | CRBNDDB1GSPT1IKZF3SMN1; SMN2 | |
| SCHEMBL30600389 | 0.90 | CRBN (0.56) | CRBNDDB1GSPT1IKZF3RAB9A | |
| SCHEMBL21751105 | 0.90 | CRBN (0.56) | CRBNDDB1GSPT1IKZF3RAB9A | |
| SCHEMBL21768342 | 0.88 | CRBN (0.51) | CRBNDDB1GSPT1IKZF3 | |
| SCHEMBL21751099 | 0.87 | CRBN (0.52) | CRBNDDB1GSPT1IKZF3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621664-B | Novel piperidine-2, 6-dione derivatives and uses thereof | 韩国化学研究院 | 2023-08-01 | — | — | CN | disclosed |