Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.62 |
| ▸ | GSPT1 | P15170 | 8/20 | 0.62 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751108 | 0.94 | CRBN (0.62) | CRBNDDB1GSPT1IKZF3EPHX2 | |
| SCHEMBL30600394 | 0.94 | CRBN (0.62) | CRBNDDB1GSPT1IKZF3EPHX2 | |
| SCHEMBL31305213 | 0.91 | CRBN (0.51) | CRBNDDB1GSPT1IKZF3MAPT | |
| SCHEMBL30600414 | 0.88 | CRBN (0.48) | CRBNDDB1GSPT1IKZF3 | |
| SCHEMBL21751073 | 0.88 | CRBN (0.48) | CRBNDDB1GSPT1IKZF3 | |
| SCHEMBL21751087 | 0.86 | CRBN (0.55) | CRBNDDB1GSPT1IKZF3RAB9A | |
| SCHEMBL30600392 | 0.86 | CRBN (0.55) | CRBNDDB1GSPT1IKZF3RAB9A | |
| SCHEMBL3655629 | 0.86 | CRBN (0.62) | CRBNDDB1GSPT1IKZF3EPHX2 | |
| SCHEMBL21751070 | 0.84 | CRBN (0.53) | CRBNDDB1GSPT1IKZF3SMN1; SMN2 | |
| SCHEMBL30600436 | 0.84 | CRBN (0.53) | CRBNDDB1GSPT1IKZF3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621664-B | Novel piperidine-2, 6-dione derivatives and uses thereof | 韩国化学研究院 | 2023-08-01 | — | — | CN | disclosed |
| EP-3623366-B9 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | KOREA RES INST CHEMICAL TECH (KR) | 2022-06-15 | — | — | EP | disclosed |
| EP-3623366-B1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | KOREA RES INST CHEMICAL TECH (KR) | 2022-01-19 | — | — | EP | disclosed |
| US-11192878-B2 | Piperidine-2,6-dione derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-12-07 | — | — | US | disclosed |
| US-11192878-B2 | Piperidine-2,6-dione derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-12-07 | — | — | US | disclosed |
| EP-3623366-A1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | Korea Research Institute of Chemical Technology (KR) | 2020-03-18 | — | — | EP | disclosed |
| US-20200062730-A1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | UBIX THERAPEUTICS, INC. (KR) | 2020-02-27 | — | — | US | disclosed |
| US-20200062730-A1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | UBIX THERAPEUTICS, INC. (KR) | 2020-02-27 | — | — | US | disclosed |
| CN-110621664-A | Novel piperidine-2, 6-dione derivatives and uses thereof | 韩国化学研究院 | 2019-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062730-A1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | CRBN, PDCD11, CD47 | CRBN 1/4885DDB1 153/4885GSPT1 2275/4885 |
| US-11192878-B2 | Piperidine-2,6-dione derivative and use thereof | CRBN, PDCD11, CD47 | CRBN 1/4885DDB1 196/4885GSPT1 2355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.