SCHEMBL30600409

SCHEMBL30600409

Cc1cc(C=O)c(C=O)cc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
TSHR P16473 2/20 0.50
ERN1 O75460 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
GRIA1 P42261 1/20 0.44
GRIA2 P42262 1/20 0.44
GRIA3 P42263 1/20 0.44
GRIA4 P48058 1/20 0.44
TDP1 Q9NUW8 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL446933 1.00 ALDH1A1 (0.50) ALDH1A1TSHRERN1SMN1; SMN2CYP1A2
SCHEMBL3687015 0.88 GRIA1 (0.52) ALDH1A1TSHRERN1SMN1; SMN2CYP1A2
SCHEMBL97117 0.88 GRIA1 (0.52) ALDH1A1TSHRERN1SMN1; SMN2CYP1A2
SCHEMBL2884919 0.87 GRIA1 (0.56) ALDH1A1TSHRERN1SMN1; SMN2CYP1A2
SCHEMBL19255286 0.87 ALDH1A1 (0.41) ALDH1A1TSHRERN1SMN1; SMN2CYP1A2
SCHEMBL686656 0.85 CYP1A2 (0.55) ALDH1A1TSHRERN1SMN1; SMN2CYP1A2
SCHEMBL23049567 0.81 TDP1 (0.48) ALDH1A1TSHRERN1SMN1; SMN2CYP1A2
SCHEMBL1397558 0.81 ERN1 (0.50) ALDH1A1TSHRERN1CYP1A2CYP3A4
SCHEMBL13556326 0.81 ALDH1A1 (0.41) ALDH1A1TSHRERN1SMN1; SMN2CYP1A2
SCHEMBL3204262 0.81 TSHR (0.48) ALDH1A1TSHRERN1SMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116940559-A Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2023-10-24 CN disclosed
CN-116829618-A Thermoplastic resin and optical lens comprising the same 三菱瓦斯化学株式会社 2023-09-29 CN disclosed