Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 20/20 | 0.52 |
| ▸ | TPO | P07202 | 17/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601296 | 0.85 | MPO (0.66) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL17782065 | 0.83 | MPO (0.67) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL1536581 | 0.83 | MPO (0.56) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL30601269 | 0.81 | MPO (0.72) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL30601244 | 0.80 | MPO (0.54) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL1536647 | 0.75 | MPO (0.52) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL1536808 | 0.73 | MPO (0.65) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL30749187 | 0.72 | MPO (0.63) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL30749180 | 0.72 | MPO (0.63) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL30749186 | 0.72 | MPO (0.63) | MPOTPOKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514816-A | Pyrimidinone pyrrole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |