SCHEMBL3060261

SCHEMBL3060261

OC(=S)CCc1nc2ccccc2s1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.66
RAB9A P51151 2/20 0.66
SMN1; SMN2 Q16637 3/20 0.63
ALOX15 P16050 1/20 0.63
HTT P42858 1/20 0.63
L3MBTL1 Q9Y468 3/20 0.58
MAPK1 P28482 2/20 0.58
GAA P10253 1/20 0.58
MAPT P10636 4/20 0.56
ALDH1A1 P00352 3/20 0.56
LMNA P02545 1/20 0.55
UBE2T Q9NPD8 1/20 0.54
ASIC3 Q9UHC3 1/20 0.54
POLB P06746 4/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
ATM Q13315 1/20 0.52
NPC1 O15118 1/20 0.51
PDE10A Q9Y233 1/20 0.51
SLC13A5 Q86YT5 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10967736 0.90 HTT (0.73) HPGDRAB9ASMN1; SMN2ALOX15HTT
SCHEMBL10967359 0.89 HTT (0.67) HPGDRAB9ASMN1; SMN2ALOX15HTT
SCHEMBL8593944 0.88 HTT (0.65) HPGDRAB9ASMN1; SMN2ALOX15HTT
SCHEMBL1269672 0.83 SMN1; SMN2 (0.82) HPGDRAB9ASMN1; SMN2ALOX15HTT
SCHEMBL1248386 0.83 MAPT (0.59) HPGDRAB9ASMN1; SMN2ALOX15HTT
SCHEMBL29911182 0.83 MAPT (0.59) HPGDRAB9ASMN1; SMN2ALOX15HTT
SCHEMBL19372016 0.82 UBE2T (0.70) HPGDRAB9ASMN1; SMN2ALOX15HTT
SCHEMBL27984502 0.81 HPGD (0.72) HPGDRAB9ASMN1; SMN2ALOX15HTT
SCHEMBL3919004 0.79 UBE2T (0.61) HPGDRAB9ASMN1; SMN2ALOX15HTT
SCHEMBL11590976 0.79 HPGD (0.68) HPGDRAB9ASMN1; SMN2ALOX15HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108929658-B Non-water type glycol ether-based heat exchange fluid medium 张家港迪克汽车化学品有限公司 2020-12-08 CN claimed
CN-105121614-B Water-soluble cutting fluid for fixed abrasive wire saw, method for cutting ingot using same, and substrate for electronic material obtained therefrom 帕莱斯化学株式会社 2020-04-17 CN claimed
CN-1910237-B Volatile corrosion inhibitor, and forming material and formed article using the same CHUBU CHELEST CO LTD 2011-09-07 CN claimed
US-20070145334-A1 Volatile corrosion inhibitor and molding material and molded article using the same CHUBU CHELEST CO., LTD. (JP) 2007-06-28 US claimed
CN-1910237-A Volatile corrosion inhibitor, and forming material and formed article using the same CHUBU CHELEST CO LTD (JP) 2007-02-07 CN claimed
JP-10287515-A None JP disclosed
JP-9176531-A None JP disclosed
CN-116606685-A Water-soluble temper rolling liquid composition for non-degreased annealed steel sheet 大同化学株式会社 2023-08-18 CN disclosed
CN-108929658-B Non-water type glycol ether-based heat exchange fluid medium 张家港迪克汽车化学品有限公司 2020-12-08 CN disclosed
CN-108929658-B Non-water type glycol ether-based heat exchange fluid medium 张家港迪克汽车化学品有限公司 2020-12-08 CN disclosed
CN-105121614-B Water-soluble cutting fluid for fixed abrasive wire saw, method for cutting ingot using same, and substrate for electronic material obtained therefrom 帕莱斯化学株式会社 2020-04-17 CN disclosed
US-8883045-B2 Metal nanowire-containing composition, and transparent conductor FUJIFILM CORPORATION (JP) 2014-11-11 US disclosed
JP-H10287515-A HERBICIDE COMPOSITION FOR PADDY FIELD RHONE POULENC YUKA AGURO KK 1998-10-27 JP disclosed
JP-H09176531-A INK FOR JET PRINTER DAINIPPON INK & CHEM INC 1997-07-08 JP disclosed
EP-0161219-B1 HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS CIBA-GEIGY AG (CH) 1991-06-12 EP disclosed
US-4741847-A Aqueous anti-corrosion agent containing an ammonium salt of 2-benzthiazolythiocarboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-03 US disclosed
US-4696763-A PAINTS, BLENDS CIBA-GEIGY CORPORATION (US) 1987-09-29 US disclosed
EP-0192132-A2 Aqueous anticorrosive agent containing an ammonium salt of 2-benzothia-zolylthiocarboxylic acid HOECHST ITALIA S.p.A. (IT) 1986-08-27 EP disclosed
EP-0161219-A2 Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed
EP-0137426-A2 2-Mercaptothiazole derivatives, process for their preparation and utilization of 2-mercaptothiazole derivatives in pharmaceutical compounds BAYER AG (DE) 1985-04-17 EP disclosed