Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593944 | 0.98 | HTT (0.65) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| SCHEMBL10967736 | 0.95 | HTT (0.73) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| SCHEMBL3060261 | 0.89 | HPGD (0.66) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| SCHEMBL6645560 | 0.85 | SMN1; SMN2 (0.91) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| SCHEMBL7835167 | 0.84 | SMN1; SMN2 (0.89) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| SCHEMBL7835431 | 0.84 | SMN1; SMN2 (0.89) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| SCHEMBL27509034 | 0.84 | SMN1; SMN2 (0.68) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| Methane SCHEMBL7997331 | 0.82 | SMN1; SMN2 (0.86) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| Bromide SCHEMBL11522514 | 0.82 | SMN1; SMN2 (0.66) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| SCHEMBL4703104 | 0.82 | HTT (0.71) | HTTALOX15SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137426-A2 | 2-Mercaptothiazole derivatives, process for their preparation and utilization of 2-mercaptothiazole derivatives in pharmaceutical compounds | BAYER AG (DE) | 1985-04-17 | — | — | EP | disclosed |