Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20939467 | 1.00 | KRAS (0.40) | KRASNR3C1TP53MAPTMEN1 | |
| SCHEMBL22584459 | 1.00 | KRAS (0.40) | KRASNR3C1TP53MAPTMEN1 | |
| SCHEMBL22584461 | 1.00 | KRAS (0.40) | KRASNR3C1TP53MAPTMEN1 | |
| SCHEMBL20939437 | 0.86 | KRAS (0.38) | KRASNR3C1TP53MAPTMEN1 | |
| SCHEMBL22584365 | 0.86 | KRAS (0.38) | KRASNR3C1TP53MAPTMEN1 | |
| SCHEMBL22584363 | 0.86 | KRAS (0.38) | KRASNR3C1TP53MAPTMEN1 | |
| SCHEMBL17731773 | 0.80 | MEN1 (0.43) | KRASNR3C1TP53MAPTMEN1 | |
| SCHEMBL30610187 | 0.80 | MEN1 (0.43) | KRASNR3C1TP53MAPTMEN1 | |
| SCHEMBL20699375 | 0.78 | TP53 (0.43) | KRASNR3C1TP53MAPTMEN1 | |
| SCHEMBL30161908 | 0.78 | TP53 (0.43) | KRASNR3C1TP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601808-B | Heterocyclic compounds and compositions and methods of use thereof | 捷思英达医药技术（上海）有限公司 | 2023-09-08 | — | — | CN | disclosed |