Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.79 |
| ▸ | DHODH | Q02127 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604082 | 1.00 | KDM4E (0.79) | KDM4EDHODHMEN1KMT2AHTT | |
| SCHEMBL1133916 | 0.88 | KDM4E (1.00) | KDM4EDHODHMEN1KMT2AHTT | |
| SCHEMBL17395204 | 0.88 | KDM4E (0.64) | KDM4EDHODHSMN1; SMN2LMNAMAPT | |
| SCHEMBL30604167 | 0.87 | PLA2G2A (0.61) | KDM4EDHODHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30604170 | 0.87 | PLA2G2A (0.61) | KDM4EDHODHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30604142 | 0.84 | KDM4E (0.56) | KDM4EDHODHHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30604143 | 0.84 | KDM4E (0.56) | KDM4EDHODHHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17584805 | 0.83 | KDM4E (0.65) | KDM4EMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL8649365 | 0.82 | KDM4E (0.77) | KDM4EDHODHMEN1KMT2AHTT | |
| SCHEMBL16431372 | 0.81 | KDM4E (0.54) | KDM4EMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |