Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605848 | 0.87 | GRM2 (0.36) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL27085985 | 0.83 | GRM2 (0.41) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL31459127 | 0.73 | AR (0.31) | — | |
| SCHEMBL30605849 | 0.70 | CLK4 (0.42) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL21200740 | 0.70 | GRM2 (0.35) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL30598890 | 0.70 | GRM2 (0.35) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL27086002 | 0.69 | GRM2 (0.40) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL30004086 | 0.68 | GRM2 (0.42) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL27086356 | 0.68 | GRM2 (0.42) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL27086522 | 0.67 | CLK4 (0.44) | KDRPIM1ROCK1CLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888112-A | Lactams as CBL-B inhibitors | 基因泰克公司 | 2023-10-13 | — | — | CN | disclosed |