Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.41 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.41 |
| ▸ | CHRNA6 | Q15825 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30606198 | 0.89 | HPGD (0.55) | SMN1; SMN2HPGDALDH1A1TSHRBCHE | |
| SCHEMBL12060676 | 0.86 | ALDH1A1 (0.55) | SMN1; SMN2HPGDALDH1A1TSHRBCHE | |
| SCHEMBL28231420 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CHRNB2CHRNA4BCHE | |
| SCHEMBL30606195 | 0.83 | POLB (0.50) | SMN1; SMN2ALDH1A1BCHEPDK2LMNA | |
| SCHEMBL21424047 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1BCHEPDK2 | |
| SCHEMBL23011862 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1BCHEPDK2 | |
| SCHEMBL29543193 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDALDH1A1BCHEPTPN1 | |
| SCHEMBL29789521 | 0.82 | RECQL (0.48) | SMN1; SMN2ALDH1A1BCHEPDK2 | |
| SCHEMBL30778396 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1CHRNB2CHRNA4BCHE | |
| SCHEMBL31391933 | 0.79 | BCHE (0.42) | SMN1; SMN2ALDH1A1BCHEPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116916924-A | MALT1 modulators and uses thereof | 稀有生物科学股份有限公司 | 2023-10-20 | — | — | CN | disclosed |