Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 1/20 | 0.45 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | VDR | P11473 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25335220 | 0.81 | OSBP (0.56) | OSBPOSBP2USP2VDRGRIN1 | |
| SCHEMBL25335224 | 0.81 | OSBP (0.56) | OSBPOSBP2USP2VDRGRIN1 | |
| SCHEMBL30606485 | 0.81 | OSBP (0.49) | OSBPOSBP2USP2VDRNFKB1 | |
| SCHEMBL25337887 | 0.79 | OSBP (0.63) | OSBPOSBP2VDRGRIN1GRIN2A | |
| SCHEMBL25337801 | 0.77 | NPC1L1 (0.48) | OSBPOSBP2USP2VDRNFKB1 | |
| SCHEMBL25337802 | 0.77 | NPC1L1 (0.48) | OSBPOSBP2USP2VDRNFKB1 | |
| SCHEMBL31504630 | 0.76 | NPC1L1 (0.49) | OSBPOSBP2USP2VDRNFKB1 | |
| SCHEMBL11786829 | 0.76 | USP2 (0.51) | OSBPOSBP2USP2VDRNFKB1 | |
| SCHEMBL11786843 | 0.76 | USP2 (0.51) | OSBPOSBP2USP2VDRNFKB1 | |
| SCHEMBL19197390 | 0.73 | USP2 (0.52) | USP2VDRGPBAR1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154193-A1 | STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Cholesgen (Shanghai) Co., Ltd. (CN) | 2025-05-15 | — | — | US | disclosed |
| WO-2023143399-A1 | STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154193-A1 | STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SREBF1, SREBF2, CYP46A1 | OSBP 80/4885OSBP2 151/4885USP2 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.