Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 2/20 | 0.56 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.56 |
| ▸ | NPC1L1 | Q9UHC9 | 6/20 | 0.51 |
| ▸ | VDR | P11473 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | CRYAB | P02511 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25335220 | 1.00 | OSBP (0.56) | OSBPOSBP2NPC1L1VDRUSP2 | |
| SCHEMBL25337262 | 0.83 | OSBP (0.66) | OSBPOSBP2NPC1L1VDRNR1H3 | |
| SCHEMBL30606530 | 0.81 | OSBP (0.45) | OSBPOSBP2NPC1L1VDRUSP2 | |
| SCHEMBL11785339 | 0.80 | VDR (0.75) | OSBPOSBP2VDRUSP2CDC25A | |
| SCHEMBL6387158 | 0.80 | VDR (0.75) | OSBPOSBP2VDRUSP2CDC25A | |
| SCHEMBL27506889 | 0.79 | OSBP (0.66) | OSBPOSBP2NPC1L1VDRNR1H3 | |
| SCHEMBL31504633 | 0.79 | OSBP (0.55) | OSBPOSBP2NPC1L1VDRUSP2 | |
| SCHEMBL11788002 | 0.78 | NPC1L1 (0.56) | OSBPOSBP2NPC1L1VDRUSP2 | |
| SCHEMBL6393234 | 0.78 | NPC1L1 (0.56) | OSBPOSBP2NPC1L1VDRUSP2 | |
| SCHEMBL5070148 | 0.77 | CDC25A (0.54) | OSBPOSBP2NPC1L1VDRNR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143399-A1 | STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |