Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.84 |
| ▸ | MAPT | P10636 | 2/20 | 0.84 |
| ▸ | NAAA | Q02083 | 13/20 | 0.72 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19617560 | 1.00 | TP53 (0.84) | TP53MAPTNAAAHCRTR2HCRTR1 | |
| SCHEMBL19617548 | 0.88 | NAAA (0.75) | TP53MAPTNAAAHCRTR2HCRTR1 | |
| SCHEMBL30607206 | 0.87 | NAAA (0.74) | TP53MAPTNAAAHCRTR2HCRTR1 | |
| SCHEMBL19617870 | 0.87 | NAAA (0.74) | TP53MAPTNAAAHCRTR2HCRTR1 | |
| SCHEMBL30607208 | 0.85 | NAAA (0.72) | TP53MAPTNAAAHCRTR2HCRTR1 | |
| SCHEMBL19617772 | 0.85 | NAAA (0.72) | TP53MAPTNAAAHCRTR2HCRTR1 | |
| SCHEMBL19617831 | 0.84 | NAAA (1.00) | TP53MAPTNAAA | |
| SCHEMBL30607187 | 0.84 | NAAA (1.00) | TP53MAPTNAAA | |
| SCHEMBL19617684 | 0.83 | MAPT (0.71) | TP53MAPTNAAALMNANPC1 | |
| SCHEMBL30607199 | 0.82 | NAAA (1.00) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476616-B | Piperazinyl methanone NAAA inhibitors | 加利福尼亚大学董事会 | 2023-10-13 | — | — | CN | disclosed |