SCHEMBL30607196

SCHEMBL30607196

CCS(=O)(=O)c1ccccc1C(=O)N1CCN(c2nc3cc(F)ccc3s2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19617755 1.00 NAAA (1.00) NAAA
SCHEMBL30607199 0.93 NAAA (1.00) NAAA
SCHEMBL19617809 0.93 NAAA (1.00) NAAA
SCHEMBL26830851 0.90 NAAA (0.81) NAAA
SCHEMBL19630639 0.88 NAAA (0.78) NAAA
SCHEMBL19617803 0.88 NAAA (1.00) NAAA
SCHEMBL30607188 0.88 NAAA (1.00) NAAA
SCHEMBL30607203 0.86 NAAA (1.00) NAAA
SCHEMBL19617716 0.86 NAAA (1.00) NAAA
SCHEMBL19630620 0.86 NAAA (0.88) NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476616-B Piperazinyl methanone NAAA inhibitors 加利福尼亚大学董事会 2023-10-13 CN disclosed