SCHEMBL30607367

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)C(C)C)[C@@H](C)O)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	3/20	0.60

▸	GLP1R	P43220	1/20	0.58

▸	CRHR1	P34998	1/20	0.57

▸	CRHR2	Q13324	1/20	0.57

▸	APLNR	P35414	2/20	0.56

▸	NPY2R	P49146	8/20	0.55

▸	NPY4R	P50391	8/20	0.55

▸	NPY5R	Q15761	8/20	0.55

▸	NPY1R	P25929	6/20	0.55

▸	KEAP1	Q14145	1/20	0.54

▸	CTSL	P07711	1/20	0.54

▸	CTSH	P09668	1/20	0.54

▸	CTSS	P25774	1/20	0.54

▸	CTSK	P43235	1/20	0.54

▸	MAPK8	P45983	1/20	0.53

▸	MAPK9	P45984	1/20	0.53

▸	MAPK10	P53779	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30567779	0.90	CALCR (0.64)	CALCRGLP1RCRHR1CRHR2APLNR
SCHEMBL30168747	0.89	CALCR (0.60)	CALCRGLP1RCRHR1CRHR2APLNR
SCHEMBL31182765	0.88	CALCR (0.62)	CALCRGLP1RCRHR1CRHR2APLNR
SCHEMBL30495724	0.88	CALCR (0.66)	CALCRGLP1RCRHR1CRHR2APLNR
SCHEMBL31182688	0.88	CALCR (0.71)	CALCRGLP1RCRHR1CRHR2NPY2R
SCHEMBL30658233	0.87	CALCR (0.71)	CALCRGLP1RCRHR1CRHR2NPY2R
SCHEMBL30429675	0.87	CALCR (0.69)	CALCRGLP1RCRHR1CRHR2NPY2R
SCHEMBL31182808	0.87	CALCR (0.69)	CALCRGLP1RCRHR1CRHR2APLNR
SCHEMBL31419713	0.87	CALCR (0.73)	CALCRGLP1RCRHR1CRHR2NPY2R
SCHEMBL31182609	0.87	CALCR (0.71)	CALCRGLP1RCRHR1CRHR2NPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed