SCHEMBL30607441

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.64

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK8	P45983	1/20	0.64

▸	MAPK9	P45984	1/20	0.64

▸	MAPK10	P53779	1/20	0.64

▸	NPY2R	P49146	10/20	0.62

▸	NPY1R	P25929	10/20	0.62

▸	NPY4R	P50391	8/20	0.62

▸	NPY5R	Q15761	8/20	0.62

▸	EPHA2	P29317	2/20	0.56

▸	EP300	Q09472	1/20	0.56

▸	HIF1A	Q16665	1/20	0.56

▸	RAMP3	O60896	1/20	0.54

▸	CALCR	P30988	1/20	0.54

▸	TFPI	P10646	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31430940	0.93	NPY2R (0.60)	MAPK8MAPK9MAPK10NPY2RNPY1R
SCHEMBL29545383	0.92	MAPK8 (0.67)	MAPK8MAPK9MAPK10NPY2RNPY1R
SCHEMBL30826816	0.90	MAPK8 (0.65)	MAPK8MAPK9MAPK10NPY2RNPY1R
SCHEMBL30846537	0.90	MAPK8 (0.62)	MAPK8MAPK9MAPK10NPY2RNPY1R
SCHEMBL30436942	0.90	MAPK8 (0.70)	MAPK8MAPK9MAPK10NPY2RNPY1R
SCHEMBL31005063	0.89	NPY2R (0.62)	MAPK8MAPK9MAPK10NPY2RNPY1R
SCHEMBL31182907	0.89	NPY2R (0.66)	MAPK8MAPK9MAPK10NPY2RNPY1R
SCHEMBL31005056	0.88	NPY2R (0.64)	MAPK8MAPK9MAPK10NPY2RNPY1R
SCHEMBL30607358	0.88	NPY2R (0.69)	MAPK8MAPK9MAPK10NPY2RNPY1R
SCHEMBL29679864	0.87	MAPK8 (0.62)	MAPK8MAPK9MAPK10NPY2RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed