SCHEMBL30607358

CC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)CC)C(C)C)C(C)C)[C@@H](C)O

nearest known ligand 0.69

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	9/20	0.69

▸	NPY4R	P50391	9/20	0.69

▸	NPY5R	Q15761	9/20	0.69

▸	NPY1R	P25929	9/20	0.69

▸	MAPK8	P45983	1/20	0.62

▸	MAPK9	P45984	1/20	0.62

▸	MAPK10	P53779	1/20	0.62

▸	EP300	Q09472	1/20	0.62

▸	HIF1A	Q16665	1/20	0.62

▸	EPHA2	P29317	2/20	0.58

▸	KDM1A	O60341	1/20	0.57

▸	RAMP3	O60896	1/20	0.57

▸	CALCR	P30988	1/20	0.57

▸	TFPI	P10646	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31005056	0.91	NPY2R (0.64)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL31182907	0.91	NPY2R (0.66)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30607456	0.89	NPY2R (0.70)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30607416	0.89	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL31005063	0.89	NPY2R (0.62)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30522300	0.89	EPHA2 (0.62)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30658285	0.89	NPY2R (0.72)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30495647	0.88	NPY2R (0.77)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30607441	0.88	MAPK8 (0.64)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL29973182	0.88	NPY1R (0.69)	NPY2RNPY4RNPY5RNPY1RMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed