SCHEMBL29407944

SCHEMBL29407944

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)CN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ VIPR2 P41587 9/20 0.62
▸ VIPR1 P32241 8/20 0.62
▸ TFPI P10646 1/20 0.59
▸ NPY1R P25929 4/20 0.56
▸ NPY2R P49146 4/20 0.56
▸ NPY4R P50391 4/20 0.56
▸ NPY5R Q15761 4/20 0.56
▸ HRAS P01112 1/20 0.54
▸ KRAS P01116 1/20 0.54
▸ SOS1 Q07889 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30463855 0.94 VIPR1 (0.66) VIPR2VIPR1TFPINPY1RNPY2R
SCHEMBL30150683 0.91 VIPR2 (0.59) VIPR2VIPR1TFPINPY1RNPY2R
SCHEMBL30607476 0.91 TFPI (0.67) VIPR2VIPR1TFPINPY1RNPY2R
SCHEMBL31031604 0.90 NPY4R (0.63) VIPR2VIPR1TFPINPY1RNPY2R
SCHEMBL30719468 0.90 TFPI (0.60) VIPR2VIPR1TFPIHRASKRAS
SCHEMBL29657455 0.90 TFPI (0.61) VIPR2VIPR1TFPIHRASKRAS
SCHEMBL30176441 0.89 TFPI (0.64) VIPR2VIPR1TFPINPY1RNPY2R
SCHEMBL29634728 0.88 TFPI (0.61) VIPR2VIPR1TFPIKRAS
SCHEMBL29519384 0.88 TFPI (0.68) VIPR2VIPR1TFPINPY1RNPY2R
SCHEMBL31115950 0.88 NPY4R (0.69) NPY1RNPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12483047-B2 Compositions and methods for treating and preventing macular degeneration GENZYME CORPORATION (US) 2025-11-25 — — US claimed
US-20220288232-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING MACULAR DEGENERATION GENZYME CORPORATION 2022-09-15 — — US claimed
EP-3600372-B1 SYNTHEKINE COMPOSITIONS AND METHODS OF USE UNIV LELAND STANFORD JUNIOR (US) 2026-05-13 — — EP disclosed
US-20260109972-A1 High-Throughput Discovery of Multi-Partite CRISPR-Based Editors UNIV CALIFORNIA (US) 2026-04-23 — — US disclosed
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) UNIV LELAND STANFORD JUNIOR (US) 2026-02-19 — — US disclosed
US-12483047-B2 Compositions and methods for treating and preventing macular degeneration GENZYME CORPORATION (US) 2025-11-25 — — US disclosed
US-20250304702-A1 WNT SIGNALING AGONIST MOLECULES UNIVERSITY OF WASHINGTON 2025-10-02 — — US disclosed
US-20250283088-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING MACULAR DEGENERATION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2025-09-11 — — US disclosed
EP-4599057-A1 HIGH-THROUGHPUT DISCOVERY OF MULTI-PARTITE CRISPR-BASED EDITORS The Regents of University of California (US) 2025-08-13 — — EP disclosed
US-20250250329-A1 CYTOKINE ADAPTOR PROTEINS AND USES THEREOF HOWARD HUGHES MEDICAL INSTITUTE 2025-08-07 — — US disclosed
US-12344842-B2 Compositions and methods for treating and preventing macular degeneration GENZYME CORPORATION (US) 2025-07-01 — — US disclosed
WO-2023143619-A1 NEUTRALIZING BLOCKING AGENT FOR BLOCKING INFECTION OF CELL BY VIRUS, PREPARATION METHOD THEREFOR AND USE THEREOF 康码(上海)生物科技有限公司 2023-08-03 — — WO disclosed
EP-4217000-A1 POTENT BINDING AGENTS FOR ACTIVATION OF THE HEDGEHOG SIGNALING PATHWAY The Board of Trustees of the Leland Stanford Junior University (US) 2023-08-02 — — EP disclosed
EP-4219564-A1 WNT SIGNALING AGONIST MOLECULES The Board of Trustees of the Leland Stanford Junior University (US) 2023-08-02 — — EP disclosed
US-20230183359-A1 WNT SIGNALING AGONIST MOLECULES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-06-15 — — US disclosed
EP-3191526-B1 WNT SIGNALING AGONIST MOLECULES UNIV LELAND STANFORD JUNIOR (US) 2023-02-22 — — EP disclosed
EP-2968461-B1 FUSION PROTEINS COMPRISING PDGF AND VEGF BINDING PORTIONS AND METHODS OF USING THEREOF GENZYME CORP (US) 2022-09-21 — — EP disclosed
US-20220288232-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING MACULAR DEGENERATION GENZYME CORPORATION 2022-09-15 — — US disclosed
WO-2022067178-A1 POTENT BINDING AGENTS FOR ACTIVATION OF THE HEDGEHOG SIGNALING PATHWAY THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-03-31 — — WO disclosed
US-20220064262-A1 FUSION PROTEINS COMPRISING PDGF AND VEGF BINDING PORTIONS AND METHODS OF USING THEREOF GENZYME CORPORATION (US) 2022-03-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250250329-A1 CYTOKINE ADAPTOR PROTEINS AND USES THEREOF IL6ST, TNFRSF1A, TRAF6 VIPR2 2752/4885VIPR1 2299/4885TFPI 3299/4885
US-20260109972-A1 High-Throughput Discovery of Multi-Partite CRISPR-Based Editors CPSF6, CPSF1, ZFR VIPR2 3485/4885VIPR1 3693/4885TFPI 4385/4885
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) ADAR, ZFR, SLIRP VIPR2 2038/4885VIPR1 1401/4885TFPI 3858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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