Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590200 | 0.84 | EDNRA (0.62) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL15012161 | 0.83 | NPC1 (0.61) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL30780353 | 0.82 | NPC1 (0.63) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL10439862 | 0.80 | TTR (0.46) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL11501126 | 0.78 | NPC1 (0.55) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL30608270 | 0.78 | NPC1 (0.66) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL11097183 | 0.77 | KDM1A (0.43) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11500841 | 0.77 | NPC1 (0.53) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL31384138 | 0.74 | MCL1 (0.71) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL3699309 | 0.73 | SMN1; SMN2 (0.69) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874452-A | Synthesis method for synthesizing 2-methylbenzofuran structural compound by taking calcium carbide as alkynyl source | 宁夏大学 | 2023-10-13 | — | — | CN | disclosed |