SCHEMBL30780353

SCHEMBL30780353

Nc1c(C(=O)c2ccccc2)oc2cccc(Cl)c12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.63
MAPT P10636 7/20 0.63
KMT2A Q03164 3/20 0.63
RAB9A P51151 8/20 0.57
SMN1; SMN2 Q16637 7/20 0.57
POLB P06746 1/20 0.57
ADORA2A P29274 1/20 0.51
CASP1 P29466 1/20 0.51
AHR P35869 1/20 0.50
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 5/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
MEN1 O00255 2/20 0.47
HPGD P15428 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
PTPN1 P18031 1/20 0.45
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26819936 0.82 NPC1 (0.63) NPC1MAPTKMT2ARAB9ASMN1; SMN2
SCHEMBL30608271 0.82 NPC1 (0.59) NPC1MAPTKMT2ARAB9ASMN1; SMN2
SCHEMBL9432830 0.81 ALDH1A1 (0.51) NPC1MAPTKMT2ARAB9ASMN1; SMN2
SCHEMBL10439862 0.80 TTR (0.46) NPC1MAPTKMT2ARAB9ASMN1; SMN2
SCHEMBL31539944 0.78 MAPK14 (0.45) NPC1MAPTKMT2ARAB9ASMN1; SMN2
SCHEMBL429754 0.78 MAPT (1.00) NPC1MAPTKMT2ARAB9ASMN1; SMN2
SCHEMBL4338832 0.76 KDM4E (0.61) SMN1; SMN2POLBAHRKDM4EALDH1A1
SCHEMBL16795004 0.74 NPC1 (0.71) NPC1MAPTKMT2ARAB9ASMN1; SMN2
SCHEMBL1869991 0.73 NPC1 (1.00) NPC1MAPTKMT2ARAB9ASMN1; SMN2
SCHEMBL16794802 0.72 NPC1 (0.72) NPC1MAPTKMT2ARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724542-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2026-04-15 EP disclosed
US-20260047265-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2026-02-12 US disclosed
EP-4573098-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2025-06-25 EP disclosed
EP-4573099-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2025-06-25 EP disclosed
WO-2024251699-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-12-12 WO disclosed
WO-2024038068-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-02-22 WO disclosed
WO-2024038029-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260047265-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES LEF1, DDT, MLLT1 NPC1 4034/4885MAPT 3943/4885KMT2A 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.