Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121523 | 0.83 | PLG (0.42) | PLGMAPTKDM1AP2RY14HTR2C | |
| SCHEMBL7121518 | 0.83 | PLG (0.42) | PLGMAPTKDM1AP2RY14HTR2C | |
| SCHEMBL7121516 | 0.83 | PLG (0.42) | PLGMAPTKDM1AP2RY14HTR2C | |
| SCHEMBL13161383 | 0.81 | HTR3A (0.55) | PLGP2RY14HTR2C | |
| SCHEMBL5011948 | 0.81 | SLC18A3 (0.55) | PLGSMN1; SMN2P2RY14 | |
| Hydrochloric Acid SCHEMBL2159262 | 0.80 | HTR3A (0.53) | PLGP2RY14HTR2C | |
| SCHEMBL23873227 | 0.79 | HTR2C (0.46) | PLGP2RY14HTR2C | |
| SCHEMBL12488729 | 0.79 | KCNH2 (0.46) | PLGKCNH2P2RY14HTR2C | |
| SCHEMBL23858275 | 0.79 | HTR2C (0.64) | PLGKDM1AP2RY14HTR2C | |
| SCHEMBL18618469 | 0.79 | KDM1A (0.44) | PLGSMN1; SMN2KDM1AMAOBHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964034-A | Heterocyclic ring P2Y 14 Receptor antagonists | 美国卫生和人力服务部 | 2023-10-27 | — | — | CN | disclosed |