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SCHEMBL30608576

SCHEMBL30608576

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C)[C@@H](C)O

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 4/20 0.49
▸ NAA50 Q9GZZ1 1/20 0.48
▸ NTSR1 P30989 1/20 0.45
▸ CRHR1 P34998 1/20 0.44
▸ CRHR2 Q13324 1/20 0.44
▸ CALCR P30988 7/20 0.42
▸ CTSB P07858 1/20 0.42
▸ GLP1R P43220 4/20 0.41
▸ RAMP3 O60896 4/20 0.41
▸ GCGR P47871 3/20 0.41
▸ F11 P03951 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30608589 0.99 CAPN1 (0.50) CAPN1NAA50NTSR1CRHR1CRHR2
SCHEMBL30608628 0.97 NAA50 (0.50) CAPN1NAA50NTSR1CRHR1CRHR2
SCHEMBL30608619 0.97 NAA50 (0.49) CAPN1NAA50NTSR1CRHR1CRHR2
SCHEMBL30608580 0.96 CAPN1 (0.51) CAPN1NAA50NTSR1CRHR1CRHR2
SCHEMBL30608582 0.96 NAA50 (0.48) CAPN1NAA50NTSR1CRHR1CRHR2
SCHEMBL30608578 0.94 NAA50 (0.49) CAPN1NAA50NTSR1CRHR1CRHR2
SCHEMBL30608601 0.94 NAA50 (0.51) CAPN1NAA50NTSR1CRHR1CRHR2
SCHEMBL30608629 0.94 NAA50 (0.51) CAPN1NAA50NTSR1CRHR1CRHR2
SCHEMBL30608630 0.94 NAA50 (0.46) CAPN1NAA50NTSR1CRHR1CRHR2
SCHEMBL30608591 0.94 NAA50 (0.46) CAPN1NAA50NTSR1CRHR1CRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP claimed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO claimed
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP disclosed
US-20250090637-A1 METHODS OF INHIBITING CEREBRAL INFLAMMATION UNIVERSITÉ DE GENÈVE (CH) 2025-03-20 — — US disclosed
CN-112469429-B Use of CCR5 inhibitors in cancer treatment 奥立安生物技术瑞士有限责任公司 2025-02-14 — — CN disclosed
CN-112469430-B Method for inhibiting cerebral inflammation 日内瓦大学 2024-12-24 — — CN disclosed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO disclosed
EP-3813870-B1 CCR5 INHIBITOR FOR USE IN TREATING CANCER ORION Biotechnology Switzerland Sarl (CH) 2023-11-15 — — EP disclosed
EP-3813869-B1 CCR5 INHIBITOR FOR USE IN TREATING A NEUROINFLAMMATORY DISORDER THAT INVOLVES CEREBRAL INFLAMMATION UNIV GENEVE (CH) 2023-10-18 — — EP disclosed
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