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SCHEMBL30608627

SCHEMBL30608627

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 1/20 0.53
▸ GRPR P30550 5/20 0.42
▸ CTSD P07339 1/20 0.41
▸ BACE1 P56817 1/20 0.41
▸ CAPN1 P07384 2/20 0.41
▸ NTSR1 P30989 1/20 0.41
▸ APLNR P35414 1/20 0.41
▸ CRHR1 P34998 1/20 0.41
▸ CRHR2 Q13324 1/20 0.41
▸ CALCR P30988 3/20 0.40
▸ GLP1R P43220 3/20 0.39
▸ GCGR P47871 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30608629 0.97 NAA50 (0.51) NAA50GRPRCAPN1NTSR1APLNR
SCHEMBL30608595 0.97 NAA50 (0.50) NAA50GRPRCTSDBACE1CAPN1
SCHEMBL30608601 0.97 NAA50 (0.51) NAA50GRPRCTSDBACE1CAPN1
SCHEMBL30608619 0.94 NAA50 (0.49) NAA50GRPRCTSDBACE1CAPN1
SCHEMBL30608593 0.94 NAA50 (0.51) NAA50GRPRCTSDBACE1CAPN1
SCHEMBL30608609 0.94 NAA50 (0.49) NAA50GRPRCTSDBACE1CAPN1
SCHEMBL30608628 0.94 NAA50 (0.50) NAA50CTSDBACE1CAPN1NTSR1
SCHEMBL30608582 0.94 NAA50 (0.48) NAA50GRPRCTSDBACE1CAPN1
SCHEMBL30608602 0.93 NAA50 (0.48) NAA50CAPN1NTSR1APLNR
SCHEMBL30608607 0.92 NAA50 (0.53) NAA50CAPN1NTSR1APLNRCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP claimed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO claimed
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP disclosed
US-20250090637-A1 METHODS OF INHIBITING CEREBRAL INFLAMMATION UNIVERSITÉ DE GENÈVE (CH) 2025-03-20 — — US disclosed
CN-112469429-B Use of CCR5 inhibitors in cancer treatment 奥立安生物技术瑞士有限责任公司 2025-02-14 — — CN disclosed
CN-112469430-B Method for inhibiting cerebral inflammation 日内瓦大学 2024-12-24 — — CN disclosed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO disclosed
EP-3813870-B1 CCR5 INHIBITOR FOR USE IN TREATING CANCER ORION Biotechnology Switzerland Sarl (CH) 2023-11-15 — — EP disclosed
EP-3813869-B1 CCR5 INHIBITOR FOR USE IN TREATING A NEUROINFLAMMATORY DISORDER THAT INVOLVES CEREBRAL INFLAMMATION UNIV GENEVE (CH) 2023-10-18 — — EP disclosed
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