Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33319 | 0.97 | RAB9A (0.73) | RAB9ANPC1MAPTALDH1A1HPGD | |
| Iodide SCHEMBL30608803 | 0.94 | RAB9A (0.70) | RAB9ANPC1MAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2864451 | 0.94 | RAB9A (0.70) | RAB9ANPC1MAPTALDH1A1HPGD | |
| Benzene SCHEMBL28593911 | 0.92 | MAPT (0.67) | RAB9ANPC1MAPTALDH1A1HPGD | |
| Nitrogen SCHEMBL27850499 | 0.92 | RAB9A (0.67) | RAB9ANPC1MAPTALDH1A1HPGD | |
| Cyanide SCHEMBL27784338 | 0.89 | RAB9A (0.64) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL2655921 | 0.89 | NPC1 (0.64) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL22539620 | 0.89 | NPC1 (0.64) | RAB9ANPC1MAPTALDH1A1HPGD | |
| Acetonitrile SCHEMBL1027924 | 0.87 | RAB9A (0.61) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL10128977 | 0.83 | ALDH1A1 (0.57) | RAB9ANPC1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116887604-A | Laser battery and preparation method thereof | 重庆大学 | 2023-10-13 | — | — | CN | disclosed |