Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696118 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2HPGDALOX15TDP1HSD17B10 | |
| SCHEMBL5862791 | 0.95 | SMN1; SMN2 (0.72) | SMN1; SMN2HPGDALOX15TDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL29008440 | 0.93 | SMN1; SMN2 (0.68) | SMN1; SMN2HPGDALOX15TDP1HSD17B10 | |
| SCHEMBL1690435 | 0.91 | HPGD (0.68) | SMN1; SMN2HPGDALOX15TDP1HSD17B10 | |
| SCHEMBL12125320 | 0.89 | SMN1; SMN2 (0.80) | SMN1; SMN2HPGDALOX15TDP1POLB | |
| SCHEMBL9385223 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDALOX15TDP1POLB | |
| SCHEMBL8869291 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2HPGDALOX15TDP1POLB | |
| SCHEMBL18717370 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2HPGDALOX15TDP1POLB | |
| SCHEMBL9773 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2HPGDALOX15TDP1POLB | |
| SCHEMBL9384172 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDALOX15TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174960-B | Toll-like receptor modulating 4, 6-diamino-pyrido [3,2-D ] pyrimidine compounds | 吉利德科学公司 | 2023-10-10 | — | — | CN | disclosed |