Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29008440 | 0.97 | SMN1; SMN2 (0.68) | SMN1; SMN2HPGDALOX15TDP1KDM4E | |
| SCHEMBL1696118 | 0.95 | SMN1; SMN2 (0.74) | SMN1; SMN2HPGDALOX15TDP1KDM4E | |
| SCHEMBL30608941 | 0.95 | SMN1; SMN2 (0.74) | SMN1; SMN2HPGDALOX15TDP1KDM4E | |
| SCHEMBL12125320 | 0.91 | SMN1; SMN2 (0.80) | SMN1; SMN2HPGDALOX15TDP1KDM4E | |
| SCHEMBL1690435 | 0.89 | HPGD (0.68) | SMN1; SMN2HPGDALOX15TDP1CYP3A4 | |
| SCHEMBL9351419 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2HPGDALOX15TDP1KDM4E | |
| SCHEMBL21998668 | 0.85 | KMT2A (0.56) | SMN1; SMN2HPGDCYP1A2EPHX2HSD17B10 | |
| SCHEMBL21998738 | 0.85 | KMT2A (0.56) | SMN1; SMN2HPGDCYP1A2EPHX2HSD17B10 | |
| SCHEMBL21998743 | 0.85 | KMT2A (0.56) | SMN1; SMN2HPGDCYP1A2EPHX2HSD17B10 | |
| SCHEMBL2186652 | 0.85 | KMT2A (0.56) | SMN1; SMN2HPGDCYP1A2EPHX2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060752-B2 | Synthesis and use of nitrophenol resins | NEW YORK UNIVERSITY (US) | 2006-06-13 | — | — | US | disclosed |
| US-20040087726-A1 | Synthesis and use of nitrophenol resins | NEW YORK UNIVERSITY | 2004-05-06 | — | — | US | disclosed |