Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421126 | 0.79 | EPHX1 (0.33) | — | |
| SCHEMBL7386041 | 0.67 | TSHR (0.38) | HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL6230962 | 0.67 | — | — | |
| SCHEMBL30468500 | 0.66 | KMT2A (0.34) | PTGS1PTGS2HPGDKMT2AMT-CO2 | |
| SCHEMBL28840555 | 0.62 | — | — | |
| SCHEMBL11594364 | 0.62 | PTGS1 (0.35) | PTGS1PTGS2HPGDKMT2AMEN1 | |
| SCHEMBL10572408 | 0.61 | ALDH1A1 (0.36) | PTGS1PTGS2HPGDKMT2AALDH1A1 | |
| SCHEMBL29789493 | 0.59 | HDAC8 (0.36) | HPGDKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5535025 | 0.58 | ALDH1A1 (0.48) | PTGS1PTGS2HPGDKMT2AMEN1 | |
| SCHEMBL13014942 | 0.58 | HPGD (0.56) | PTGS1PTGS2HPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110891938-B | Tetrahydro-benzo [ D ] azepine derivatives as GPR120 modulators | 卡尔丹治疗有限公司 | 2023-10-31 | — | — | CN | disclosed |